Compared to traditional antimicrobial agents such as chlorhexidine, hydrogen peroxide and
sodium hypochlorite, with their potential adverse effects, Ozone displays a safe and broad
spectrum of antimicrobial activity against bacteria, viruses, and fungi, while at the same
time promoting soft tissue healing by increasing oxygenation and increasing blood flow. This
broad range of attributes, together with Ozone being nature friendly, brings it into the
holistic sphere of treatments.
Ozonated water is used as ozone therapy, particularly in the management of periodontal
disease, root canal treatment, dental implants, and sensitivity associated with bleaching
procedures. “The use of ozonated water in cleaning and disinfecting root canals helps to
eliminate bacteria and can increase the success of root canal treatments. Additionally,
ozone has been shown to promote healing at oral surgical sites and wounds, stimulate
tissue regeneration, and improve overall healing outcomes.”
Ozone has also been applied to prevent the development or progression of caries and to
reverse early carious lesions, thanks to its remineralizing potential. It has been shown that
Ozone therapy promotes early healing while reducing post treatment discomfort, which in
turn enhances the final results for the patient.
References
Rezaeianjam, M., Khabazian, A., Khabazian, T. et al. Efficacy of ozone therapy in dentistry
with approach of healing, pain management, and therapeutic outcomes: a systematic
review of clinical trials. BMC Oral Health 25, 433 (2025). https://doi.org/10.1186/s12903-
025-05790-0
Veneri, Federica & Lanteri, Valentina & Consolo, Ugo & Checchi, Vittorio & Generali, Luigi.
(2025). Ozone in Dentistry: An Updated Overview of Current Applications and Future
Perspectives. Current Oral Health Reports. 12. 10.1007/s40496-024-00395-y.
